Synthesis of Casein-Related Peptides and Phosphopeptides. VII. The efficient Synthesis of Ser(P)-Containing peptides by the Use of Boc-Ser(PO3R2)-OH Derivatives
A new approach to the synthesis of Ser(PO3R2)-containing peptides by using five protected Boc-Ser(PO3R2)-OH (R = phenyl, ethyl, methyl, benzyl, t-butyl) derivatives is described.The five Boc-protected derivatives are prepared by a simple three-step synthe
Perich, John W.,Alewood, Paul F.,Johns, R. B.
p. 233 - 252
(2007/10/02)
Synthesis of Casein-Related Peptides and Phosphopeptides. V The Efficient Global 'Phosphite-Triester' Phosphorylation of Protected Serine Derivatives and Peptides by Using Dibenzyl or Di-t-butyl N,N-Diethylphosphoramidite.
Both dibenzyl N,N-diethylphosphoramidite and di-t-butyl N,N-diethylphosphoramidite are shown to be suitable reagents for the efficient 1H-tetrazole-catalysed 'phosphite-triester' phosphorylation of the protected serine derivative Boc-Ser-OCH2C6H4NO2-p. Bo
Perich, John W.,Johns, R. B.
p. 1623 - 1632
(2007/10/02)
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