- Adenosine receptor antagonists
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The invention provides a compound shown as a formula (I) and a pharmaceutical composition thereof. The compounds of formula (I) of the present invention are useful as adenosine receptor inhibitors, especially A2A and/or A2B inhibitors, for example, the product can be used for prevention or treatment of diseases associated with A2A and/or A2B activity or expression.
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Paragraph 0117-0120
(2020/12/15)
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- Adenosine receptor antagonist
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The invention provides a compound shown as a formula (I) and a pharmaceutical composition thereof. The compound of formula (I) of the present invention is useful as adenosine receptor inhibitors, especially A2A and/or A2B inhibitors, for example, in the prevention or treatment of diseases associated with A2A and/or A2B activity or expression.
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Paragraph 0115-0117
(2020/11/09)
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- P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS
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The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R4 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient.
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Paragraph 0231; 0232
(2015/07/07)
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- TETRACENE DERIVATIVE AND METHOD FOR SYNTHESIZING THE SAME, AND ORGANIC ELECTRONICS DEVICE PREPARED USING THE SAME
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PROBLEM TO BE SOLVED: To provide a tetracene derivative having an aromatic heterocycle in a side chain, as a novel compound which can be used as a coating type organic semiconductor material, and a method for synthesizing the same, and an organic electronics device prepared using the same. SOLUTION: This invention provides a tetracene derivative represented by formula (1) (X is O, S, Se or N; and R1 and R2 are H, a linear or branched alkyl group, F, Cl, Br, an alkyl group comprising at least one Br, an aryl group, a heterocycle group, a hydroxy group, an ether group or an amino group. COPYRIGHT: (C)2016,JPO&INPIT
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Paragraph 0092-0094
(2016/10/08)
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- Oxidative Substitution Reactions of Organostannyl Compounds with Lead Tetraacetate. A Convenient Route to 5-Alkylidene-2(5H)-furanones
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5-Substituted 2-tributylstannylfurans which were synthesized by the reaction of corresponding 5-substituted 2-lithiofurans with tribitylstannyl chloride, were treated with two equimolar amounts of lead tetraacetate at room temperature to give corresponding 5-substituted 5-acetoxy-2(5H)-furanones in good yields.The 5-acetoxy-2(5H)-furanone was heated at 80 deg C in acetic acid-acetic anhydride containing a catalytic amount of concentrated sulfuric acid to give 5-alkylidene-2(5H)-furanone in moderate yield.
- Yamamoto, Makoto,Munakata, Hiroshi,Kishikawa, Keiki,Kohmoto, Shigeo,Yamada, Kazutoshi
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p. 2366 - 2370
(2007/10/02)
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