Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies
A novel synthetic route and anti-HIV activity evaluation of a new series of 2-(4-(2,4-dibromophenyl)-1,2,3-thiadiazol-5-ylthio)acetamide (TTA) derivatives are described. Bioactivity assay indicated that most of the title compounds showed good activities a
Zhan, Peng,Liu, Xinyong,Li, Zhenyu,Fang, Zengjun,Li, Zhong,Wang, Defeng,Pannecouque, Christophe,Clercq, Erik De
experimental part
p. 5920 - 5927
(2009/12/24)
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