New Methods for the Preparation of 2-Formyl-1,2,3,4-tetrahydroisoquinolines via N-Formyliminium Ions
N-Formyl-2-phenylethylamines react with different aldehydes in acidic medium giving good yields of 2-formyl-1,2,3,4-tetrahydroisoquinolines.In situ prepared N-formyl-2-phenylethylamine (from phenethylamines in formic acid as the reaction medium) can also be used for the synthesis of the title compounds.
Lukanov, Ludmil K.,Venkov, Athanas P.,Mollov, Nikola M.
p. 1031 - 1032
(2007/10/02)
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