Losartan-antioxidant hybrids: Novel molecules for the prevention of hypertension-induced cardiovascular damage
We report the first examples of a new series of antioxidant-sartan hybrids (AO-sartans), which were made by adding an antioxidant fragment to the hydroxymethyl side chain of losartan. Experiments performed in cultured cells demonstrate that these new hybr
García, Gonzalo,Rodríguez-Puyol, Manuel,Alajarín, Ramón,Serrano, Isabel,Sánchez-Alonso, Patricia,Griera, Mercedes,Vaquero, Juan J.,Rodríguez-Puyol, Diego,álvarez-Builla, Julio,Díez-Marqués, María L.
supporting information; experimental part
p. 7220 - 7227
(2010/08/06)
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