4-(1-benzoylindol-3-yl)butyric acids and FK143: Novel nonsteroidal inhibitors of steroid 5α-reductase (II)
A novel series of indolebutyric acids with varying benzoyl substituents were synthesized to develop nonsteroidal inhibitors of steroid 5α-reductase. We previously reported the discovery of a novel nonsteroidal 5α-reductase inhibitor, FR119680, which had a
A benzoylaminophenoxybutanoic acid derivative of general formula I or non-toxic salts thereof possess an inhibitory activity on 5alpha-reductase, and therefore be useful for treating and/or preventing agent for alopecia, acnes or prostatic hypertrophy
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(2008/06/13)
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