- A succinct synthesis of valganciclovir hydrochloride, a cytomegalovirus (CMV) retinitis inhibitor
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A concise and efficient synthesis of valganciclovir hydrochloride 1, a CMV retinitis inhibitor, without involving protection-deprotection sequences, is described. The synthetic utility of (2S)-azido-3-methylbutyric acid, which acts as a masked L-valine equivalent, is demonstrated in the synthesis of 1. ARKAT-USA, Inc.
- Babu, K. Srihari,Srinivas,Madhavi,Babu,Reddy, G. Madhusudhan,Haldar,Rao, P. Narasimha,Krishna,Srinivas,Venkateshwarulu,Reddy, P. Pratap,Anand, R. Vijaya
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p. 199 - 208
(2011/05/11)
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- PREPARATION OF VALGANCICLOVIR AND ITS SALTS
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Processes for preparing valganciclovir and pharmaceutically acceptable salts thereof, as well as intermediates for the processes.
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Page/Page column 42
(2010/04/27)
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