- Disulfide-Catalyzed Iodination of Electron-Rich Aromatic Compounds
-
Herein, a disulfide-catalyzed electrophilic iodination of aromatic compounds using 1,3-diiodo-5,5-dimethylhydantoin (DIH) has been developed. The disulfide activates DIH as a Lewis base to promote the iodination reaction in acetonitrile under mild conditions. This system is applicable to a wide range of electron-rich aromatic compounds, including acetanilide, anisole, imidazole, and pyrazole derivatives.
- Iida, Keisuke,Ishida, Shunsuke,Watanabe, Takamichi,Arai, Takayoshi
-
-
- Disulfide-Catalyzed Iodination of Electron-Rich Aromatic Compounds
-
Herein, a disulfide-catalyzed electrophilic iodination of aromatic compounds using 1,3-diiodo-5,5-dimethylhydantoin (DIH) has been developed. The disulfide activates DIH as a Lewis base to promote the iodination reaction in acetonitrile under mild conditions. This system is applicable to a wide range of electron-rich aromatic compounds, including acetanilide, anisole, imidazole, and pyrazole derivatives.
- Iida, Keisuke,Ishida, Shunsuke,Watanabe, Takamichi,Arai, Takayoshi
-
p. 7411 - 7417
(2019/06/18)
-
- Palladium-catalyzed ortho-halogenations of acetanilides with N-halosuccinimides via direct sp2 C–H bond activation in ball mills
-
A solvent-free palladium-catalyzed ortho-iodination of acetanilides using N-iodosuccinimide as the iodine source has been developed under ball-milling conditions. This present method avoids the use of hazardous organic solvents, high reaction temperature,
- Liu, Zi,Xu, Hui,Wang, Guan-Wu
-
supporting information
p. 430 - 435
(2018/02/27)
-
- The oxidative bromination and iodination of dimethylacetanilides
-
The oxidative bromination and iodination of the six dimethylacetanilides have been examined; whereas bromination of 2,4-dimethyl- and 2,6-dimethylacetanilides using potassium bromide, sodium tungstate and peracetic acid gave predominantly the 6- and 4-bro
- Medina, Inmaculada C. Rodriguez,Hanson, James R.
-
p. 428 - 429
(2007/10/03)
-
- Halogenation Using Quaternary Ammonium Polyhalides. XVII. Iodination of Acetanilide Derivatives with Benzyltrimethylammonium Dichloroiodate and Zinc Chloride
-
The reaction of acetanilide derivatives with benzyltrimethylammonium dichloroiodate in acetic acid in the presence of ZnCl2 at room temperature or at 70 deg C gave iodo-substituted acetanilide derivatives in good yields.
- Kajigaeshi, Shoji,Kakinami, Takaaki,Watanabe, Fumiko,Okamoto, Tsuyoshi
-
p. 1349 - 1351
(2007/10/02)
-