Design and synthesis of optically active esters of γ-amino-β-oxo acids as precursors for the synthesis of tetramic acids derived from L-serine, L -tyrosine, and L-threonine
Tetramic acids bearing a hydroxyalkyl or hydroxybenzyl group at C-5 of the heterocyclic ring were successfully prepared. α-Amino acids appropriately protected and activated were used as acylating agents for the C-acylation of active methylene compounds. T
Matiadis, Dimitris,Igglessi-Markopoulou, Olga
experimental part
p. 5989 - 5995
(2011/02/26)
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