Chiral amine thiourea-promoted enantioselective michael addition reactions of 3-substituted benzofuran-2(3 H)-ones to maleimides
A highly diastereo- and enantioselective Michael addition reaction with respect to prochiral 3-substituted benzofuran-2(3H)-ones and maleimides by a chiral bifunctional thiourea-tertiary amine catalyst was investigated. The corresponding adducts, containi