DIASTEREOSELECTIVITY IN THE CYCLIZATION OF 1-(2-(BENZYLOXYMETHYL)-3-BUTENYL)-5-ETHOXY-2-PYRROLIDINONES
1-(2-(Benzyloxymethyl)-3-butenyl)-5-ethoxy-2-pyrrolidinones 12 cyclize upon formic acid treatment to indolizinones.The effect of some substituents α to the iminium carbon atom on the diastereoselectivity of the cyclization is discussed.
Zonjee, Johannes N.,Koning, Henk de,Speckamp, W. Nico
p. 7553 - 7564
(2007/10/02)
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