- 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
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Compounds of the formulas STR1 wherein: Y is an alkylene bridge of 3-9 carbon atoms; R' is lower-alkyl or hydroxy-lower-alkyl of 1-5 carbon atoms; R1 and R2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and R8 is hydrogen or lower-alkyl of 1-5 carbon atoms, with the proviso that when R8 is hydrogen R' is hydroxy-lower-alkyl, are useful as antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.
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- 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
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Compounds of the formulas STR1 wherein: Y is an alkylene bridge of 1-9 carbon atoms; R' is lower-alkyl or hydroxy-lower-alkyl of 1-5 carbon atoms; R1 and R2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and R8 is hydrogen or lower-alkyl of 1-5 carbon atoms, are useful as antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.
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