- Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
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The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
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Page/Page column 180
(2008/12/05)
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- N-acylamino acid amide compounds and intermediates for preparation thereof
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The present invention discloses the compound represented by the formula (I): wherein A represents the following formula (a-1) or the following formula (a-2): B represents the following formula (b): (wherein the symbols are each as defined in the specification) or a pharmaceutically acceptable salts thereof, and intermediates for the preparation thereof, which have excellent platelet aggregation inhibitory activity and other properties and useful as prophylactic or therapeutic agents for diseases associated with a fibrinogen receptor, thrombosis, infarction and the like.
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- Gonadotropin-Releasing Hormone Antagonists: Novel Members of the Azaline B Family
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A series of antagonists of gonadotropin-releasing hormone (GnRH) homologous to azaline B (1, DCpa2, DPal3, Aph5(Atz), DAph6(Atz), ILys8, DAla10>GnRH) was synthesized, cha
- Rivier, Jean E.,Jiang, Guangcheng,Porter, John,Hoeger, Carl A.,Craig, A. Grey,et al.
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p. 2649 - 2662
(2007/10/03)
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