Bronsted acid-promoted sequential hydroarylation-hydroamidation of arene-tethered 1-(2-alkynylphenyl)ureas: Direct access to 4,4-spiro-3,4-dihydro- 2-(1H)-quinazolinones
A Bronsted acid-promoted approach to 4,4-sipro-3,4-dihydro-2-(1H)- quinazolinones from arene-tethered 1-(2-alkynylphenyl)ureas has been developed. The reaction is initiated by intramolecular hydroarylation followed by hydroamidation, assisted by intramole