Conversion of avermectin B1 to 19-epi-avermectin B1
Avermectin B1 (1) has been converted to 19-epi-avermectin B1 (2) in six steps. Analog 2 retains some bioactivity but is substantially less bioactive than 1.
Blizzard,Bostrom,Margiatto,Mrozik,Fisher
p. 2723 - 2726
(2007/10/02)
Photoisomers of Avermectins
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Mrozik, Helmut,Eskola, Philip,Reynolds, Glenn F.,Arison, Byron H.,Smith, Graham M.,Fisher, Michael H.
p. 1820 - 1823
(2007/10/02)
Studies on the deconjugation-epimerization strategy en route to avermectin B(1a): Problems and solutions
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Hanessian,Dube,Hodges
p. 7063 - 7067
(2007/10/02)
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