Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis
Over 50 phenyl thiazolyl urea and carbamate derivatives were synthesized for evaluation as new inhibitors of bacterial cell-wall biosynthesis. Many of them demonstrated good activity against MurA and MurB and gram-positive bacteria including MRSA, VRE and
Francisco, Gerardo D.,Li, Zhong,Albright, J. Donald,Eudy, Nancy H.,Katz, Alan H.,Petersen, Peter J.,Labthavikul, Pornpen,Singh, Guy,Yang, Youjun,Rasmussen, Beth A.,Lin, Yang-I.,Mansour, Tarek S.
p. 235 - 238
(2007/10/03)
Azoles. Part 10. Thiazolothienopyrimidine, a New Heterocyclic Ring System
Thienothiazoles were prepared by reaction of 4-chlorothiazole-5-carbaldehydes or 4-chlorothiazole-5-carbonitriles with either ethyl 2-mercaptoacetate or 2-mercaptoacetamide.The 6-aminothienothiazole-5-carboxamides obtained were converted int
Athmani, Salah,Iddon, Brian
p. 7689 - 7702
(2007/10/02)
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