Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4- hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7-yl]carbamate
Metabolism studies with ethyl [5-amino-1,2-dihydro-2-methyl-3- phenylpyrido[3,4-b]pyrazin-7-yl]carbamate (1) in mice were reported previously to give a hydroxylated metabolite, which was methylated to give a methoxy derivative. The metabolite and its deri
Temple Jr.,Rener
p. 988 - 993
(2007/10/02)
1,2-dihydropyrido(3,4,-b)pyrazines as fungicides
1,2-dihydropyrido[3,4-b]pyrazines are provided which possess antimitotic activity. The compounds have the structure: STR1 wherein R is a lower alkyl group and OR1 is a member selected from the group consisting of aryl-alkyl ethers having from s
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(2008/06/13)
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