Effect of catalytic alkali metal bromide on Hofmann-type rearrangement of imides
The Hofmann-type rearrangement of aromatic and aliphatic imides using KBr as the catalyst proceeded to provide aromatic and aliphatic amino acid derivatives. We have also developed a new synthetic route to gabapentin with this method.
Moriyama, Katsuhiko,Ishida, Kazuma,Togo, Hideo
supporting information; experimental part
p. 8574 - 8576
(2012/09/07)
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