- Surface control of a photoresponsive self-assembled monolayer and selective deposition of Ag Nanoparticulate Ink
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A highly hydrophobic self-assembled monolayer (SAM) with high photosensitivity to soft UV (λ = 365 nm) was formed on thermally surface-oxidized silicon wafers by a silane coupling agent bearing a 2-nitrobenzyl carbamate moiety. Very smooth SAM was obtaine
- Konishi, Tsubasa,Yamaguchi, Kazuo
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Read Online
- Experimental and Computational Studies of Palladium-Catalyzed Spirocyclization via a Narasaka-Heck/C(sp3or sp2)-H Activation Cascade Reaction
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The first synthesis of highly strained spirocyclobutane-pyrrolines via a palladium-catalyzed tandem Narasaka-Heck/C(sp3 or sp2)-H activation reaction is reported here. The key step in this transformation is the activation of a δ-C-H bond via an in situ generated σ-alkyl-Pd(II) species to form a five-membered spiro-palladacycle intermediate. The concerted metalation-deprotonation (CMD) process, rate-determining step, and energy barrier of the entire reaction were explored by density functional theory (DFT) calculations. Moreover, a series of control experiments was conducted to probe the rate-determining step and reversibility of the C(sp3)-H activation step.
- Wei, Wan-Xu,Li, Yuke,Wen, Ya-Ting,Li, Ming,Li, Xue-Song,Wang, Cui-Tian,Liu, Hong-Chao,Xia, Yu,Zhang, Bo-Sheng,Jiao, Rui-Qiang,Liang, Yong-Min
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supporting information
p. 7868 - 7875
(2021/05/27)
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- α-Methylation of Ketones with Methanol Catalyzed by Ni/SiO2-Al2O3
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α-Methylation of ketones with methanol catalyzed by a cheap and easy to handle Ni/SiO2-Al2O3 was explored. After optimization of the reaction between propiophenone and methanol, the desired product was obtained in 95 % isolated yield. A wide range of ketones was methylated under the optimized conditions (16 examples). This procedure was extended to a three-component cross-benzylation-methylation of acetophenone.
- Charvieux, Aubin,Duguet, Nicolas,Métay, Estelle
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supporting information
p. 3694 - 3698
(2019/06/13)
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- Silver-promoted cascade radical cyclization of γ,δ-unsaturated oxime esters with P(O)H compounds: synthesis of phosphorylated pyrrolines
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A cascade radical cyclization was realized for the first silver-promoted imino-phosphorylation of γ,δ-unsaturated oxime esters, which provided a step-economical and redox-neutral route to access a variety of phosphorylated pyrrolines in good to excellent yields. Moreover, a new bulky trivalent phosphine ligand with a pyrroline motif was obtained through a deoxidation process.
- Chen, Chen,Bao, Yinwei,Zhao, Jinghui,Zhu, Bolin
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supporting information
p. 14697 - 14700
(2019/12/11)
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- Copper-catalyzed iminohalogenation of γ, δ-unsaturated oxime esters with halide salts: Synthesis of 2-halomethyl pyrrolines
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A copper-catalyzed iminohalogenation of unactivated alkenes of γ, δ-unsaturated oxime esters is achieved by using readily available halide salts. Utilizing this protocol, a sequence of structurally diversiform 2-halomethyl pyrrolines are efficiently synthesized and a mechanism involving iminyl radical intermediates, which were initiated by Cu(I) species, was proposed.
- Chen, Chen,Ding, Jie,Wang, Yuebo,Shi, Xiaonan,Jiao, Dequan,Zhu, Bolin
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supporting information
(2019/08/13)
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- FLUORINE-CONTAINING COMPOUND, SUBSTRATE FOR PATTERN FORMATION, PHOTODEGRADABLE COUPLING AGENT, PATTERN FORMATION METHOD, AND COMPOUND
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A compound represented by formula (e): where R1 represents a branched chain or cyclic alkyl group having 3 to 10 carbon atoms, and Rf1 and Rf2 represent fluorinated alkoxy groups.
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Paragraph 0115-0121
(2017/06/27)
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- The cage silsesquioxane derivatives
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PROBLEM TO BE SOLVED: To provide a novel cage-shaped silsesquioxane derivative.SOLUTION: Cage-shaped silsesquioxane derivatives with formula 1 and formula 2 are disclosed. Each of R and Rto Rrepresents an alkyl group or the like, G represents -COO- or the like, Y represents an active ester group, and each of m and p represents an integer of 2 to 20.
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Paragraph 0091; 0092
(2017/11/08)
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- Substituent effects at the benzyl position and aromatic ring of silane-coupling agents containing 2-nitrobenzyl esters on photosensitivity and hydrophobic surface of a self-assembled monolayer (SAM)
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Silane-coupling agents with 2-nitrobenzyl esters containing alkyl substituents at the benzyl position and alkoxy and/or fluoroalkoxy groups of the aromatic ring were synthesized to prepare a self-assembled monolayer (SAM) on quartz glass, silicon wafer and thermally oxidized silicon wafer. The resulting photosensitive SAMs before and after photoirradiation were characterized by contact angle measurement, UV spectroscopy, X-ray photoelectron spectroscopy (XPS), and X-ray reflectivity (XRR). Photosensitivity of the SAM was influenced by substituents at the benzyl position and aromatic ring as well as the irradiation conditions in air or solution and substrates employed. Silane-coupling agents with bulky substituent at the benzyl position and double fluoroalkoxy chains are preferable in terms of the photosensitivity and hydrophobic surface.
- Konishi, Tsubasa,Hashimoto, Teppei,Sato, Naoya,Nakajima, Kazuki,Yamaguchi, Kazuo
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p. 125 - 134
(2016/01/27)
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- FLOURINE-CONTAINING COMPOUND, SUBSTRATE FOR PATTERNING, PHOTODEGRADABLE COUPLING AGENT, PATTERNING METHOD, AND COMPOUND
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A fluorine-containing compound represented by General formula (1), wherein X represents a halogen atom or an alkoxy group, R1 represents a hydrogen atom or a linear, branched, or cyclic alkyl group having 1 to 10 carbon atoms, Rf1 and Rf2 are each independently a fluorinated alkoxy group, and n represents an integer of 0 or more.
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Paragraph 0120; 0121; 0122; 0123
(2016/06/28)
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- Hypervalent iodine mediated direct one pot transformation of aldehydes to ketones
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An environmentally benign, step economical synthesis of ketones directly from aldehydes has been developed using hypervalent iodine as an oxidant. The key features of this protocol are its mild conditions without the use of any heavy and toxic metals for the synthesis of a wide range of ketones. the Partner Organisations 2014.
- Sagara, Prateep Singh,Chebolu, Rajesh,Bahuguna, Ashish,Ravikumar
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p. 15011 - 15013
(2014/04/17)
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- FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE
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Conventional many fungicidal compositions have had practical problems such that either a preventive effect or a curing effect is inadequate, the residual effect tends to be inadequate, or the controlling effect against plant diseases tends to be inadequat
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Page/Page column 100
(2008/06/13)
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- Conception, characterization and correlation of new marine odorants
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Via a synthetic sequence consisting of PPA-mediated Friedel-Crafts acylation of veratrol (8), Clemmensen reduction, demethylation with TMSI, Williamson ether synthesis employing 3-chloro-2-(chloromethyl)prop-1-ene and in-situ ruthenium tetroxide oxidation, numerous substituted benzo[b][1,4]dioxepinones 15-27 and 2,3-dihydro-1H-5,9-di-oxacyclohepta[f]indenones 7, 13 and 14 were prepared to study their odor-structure correlation. In the course of these studies, we discovered the extremely powerful new marine odorant 7-(3′ -methylbutyl)benzo[b][1,4]dioxepin-3-one (16). On the basis of the measured odor threshold data, an olfactophore model was constructed that rationalizes the observed odor intensities, and indicates an aliphatic hydrophobe at a distance of 6.3 A from the centre of the aromatic-ring binding site. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
- Kraft, Philip,Eichenberger, Walter
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p. 3735 - 3743
(2007/10/03)
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- Enzyme-mediated synthesis of (S)- And (R)-verapamil
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A lipase-mediated synthesis of (S)- And (R)-verapamil is described. The key steps of the synthetic sequence are the enantioselective acetylation, mediated by Lipase PS, of allylic alcohol (Z)-(±)-2, affording the acetate derivative (Z,R)-(-)-3 (ee 92%) and the Ireland-Claisen rearrangement of this latter and of its enantiomer (Z,S)-(+)-3 (ee 92%) to afford acid derivatives (E,R)-(-)-4 (ee 94%) and (E,S)-(+)-4 (ee 93%), precursors of (S)- and (R)-verapamil, respectively.
- Brenna, Elisabetta,Fuganti, Claudio,Grasselli, Piero,Serra, Stefano
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p. 1349 - 1357
(2007/10/03)
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- Acylation of aromatic ethers/phenols
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Aromatic ethers/phenols are acylated, characteristically into hydroxy- and/or alkoxyaromatic alkylketones, and in particular, are acylated in the para-position relative to an alkoxy substituent borne by the aromatic nucleus, by reacting/condensing same with an acylation agent, for example acetyl chloride or acetic anhydride, in the presence of a catalytically effective amount of a bismuth halide, or a precursor compound that generates, in situ, a bismuth halide.
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- The catalytic Friedel-Crafts acylation reaction of aromatic compounds with carboxylic anhydrides using combined catalyst system of titanium(IV) chloride tris(trifluoromethanesulfonate) and trifluoromethanesulfonic acid
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Various aromatic ketones are prepared in good to high yields with carboxylic anhydrides using combined catalyst system of TiCl(OTf)3 and TfOH.
- Izumi, Jun,Mukaiyama, Teruaki
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p. 739 - 740
(2007/10/03)
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- Catechol diacetate derivatives for inducing the production of nerve growth factor to treat degenerative diseases in the central nervous system
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A pharmaceutical composition for the treatment of regressive disorders of the central nervous system treatable by inducing the production and secretion of nerve growth factor, containing as an active ingredient a catechol derivative of the formula STR1 where R6 is a lower alkyl group having 2 to 5 carbon atoms. The catechol derivatives provide preventative and remedial effects for regressive disorders in the central nervous system including senile dementia of the alzheimer type.
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- 2-Phenylindenes: Development of a new mammary tumor inhibiting antiestrogen by combination of estrogenic side effect lowering structural elements
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A new antiestrogenic, mammary tumor inhibiting 2-phenylindene was developed by the use of structural elements that we have shown to decrease estrogenic side effects but to increase antiestrogenic activity and retain the antitumor effect of certain stilben
- Schneider,Ball
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