A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors
Analogues of the P2 receptor antagonists pyridoxal-5'-phosphate and the 6-azophenyl-2',4'-disulfonate derivative (PPADS), in which the phosphate group was cyclized by esterification to a CH2OH group at the 4-position, were synthesized. The cycl
Jacobson, Kenneth A.,Kim, Yong-Chul,Wildman, Scott S.,Mohanram, Arvind,Harden, T. Kendall,Boyer, José L.,King, Brian F.,Burnstock, Geoffrey