cas 143254-82-4, 1-Chlorocarbonyl-4-piperidinopiperidine hydrochloride | Articles data ｜lookchem

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143254-82-4

Articles about 143254-82-4Total 4 be found

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PRO-DRUGS OF ELIGLUSTAT
The present invention is directed to pro-drugs of Eliglustat (formula A) and process for the preparation thereof. The present invention is further directed to pharmaceutical composition thereof and method of treatment using the same.
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Page/Page column 43-44

(2019/11/19)

PROCESS FOR THE MANUFACTURE OF IRINOTECAN HYDROCHLORIDE BY TOTAL SYNTHESIS
Disclosed herein is a highly safe and easily scalable process for the production of 7-Ethyl- 10-hydroxycamptothecin and its conversion to Irinotecan hydrochloride by total synthesis.
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Page/Page column 9

(2012/03/27)

PROCESS FOR PRODUCING [1,4'] BIPIPERIDINYL-1'-CARBONYL CHLORIDE OR HYDROCHLORIDE THEREOF
The present invention is related to a process for the preparation of [1,4'] bipiperidinyl-1' -carbonyl chloride or its hydrochloride using methylene chloride as a solvent in the reaction of 4-piperidinopiperidine with phosgene and removing the reaction so
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Page/Page column 4-5

(2008/06/13)

AN IMPROVED PROCESS FOR THE PREPARATION OF IRINOTECAN HYDROCHLORIDE TRIHYDRATE
The invention relates to an improved process for the preparation of Irinotecan hydrochloride trihydrate of formula (4) of enhanced yield, purity by contacting 1-chlorocarbonyl-4-piperidinopiperidine hydrochloride with 7-ethyl-10 hydroxy-camptothecin [IRT-3 (synthetic)] to obtain crude Irinotecan which is subsequently purified by solvent treatment, obtaining purified irinotecan which is converted into irinotecan hydrochloride trihydrate and the invention also relates to a report of the compound 1-chlorocorbonyl-4-iperidinopiperidine hydrochloride of formula (1) and its process for preparation.
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Page/Page column 9

(2010/10/20)

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103816-16-6
10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin

Chemical Properties

Appearance/Colour :power
Boiling Point: 344.5 °C at 760 mmHg
Flash Point:162.1 °C
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Vapor Pressure: 6.57E-05mmHg at 25°C
PSA: 23.55000
LogP: 2.97330

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