7-substituted quinolones and naphthyridones as antibacterial agents
7-Substituted quinolones and naphthyridones are described as antibacterial agents as well as a process for their manufacture, compositions therefor, wherein the 7-substituent is a pyrrolidine ring substituted at the 3-position by a substituted aromatic hydrocarbon or a heteroaromatic group.
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(2008/06/13)
3-Arylpyrrolidines via azomethine ylide 1,3-dipolar cycloaddition to styrenes
Monosubstituted olefins conjugated to an aromatic or heteroaromatic ring undergo 1,3-dipolar cycloaddition with the azomethie ylide derived from N-benzyl-N-(methoxymethyl)trimethylsilylamine to give 3-aryl- and 3-hetero-arylpyrrolidines in good to excellent yield.
Laborde, Edgardo
p. 6607 - 6610
(2007/10/02)
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