Synthetic approaches toward total synthesis of 12β-methyl- and 12-methylene-19-norpregnanes
The effect of a substituent in the 12-position of progestagens was studied. To this end, various approaches toward the preparation of 12β-alkyl- and 12-alkylidenenorpregnanes were investigated. Eventually, the desired compounds 17β-hydroxy-12β-methyl-18a-
Broess,Van Vliet,Groen,Hamersma
p. 514 - 521
(2007/10/02)
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