- Quinoline derivatives and preparation method and application thereof
-
The invention belongs to the technical field of insecticides and acaricides, and particularly relates to quinoline derivatives and a preparation method and application thereof. The invention particularly provides a compound shown as a formula (I) or salt thereof. The compound shown as the formula (I) has good activity on various pests and mites in agriculture or other fields. Moreover, the compounds can obtain a very good prevention and treatment effect at a very low dosage, so that the compounds can be used for preparing insecticides and/or acaricides. In addition, the preparation steps of the compound are simple, and the product yield is high, so that the compound has a good application prospect.
- -
-
Paragraph 0151-0153
(2020/06/16)
-
- COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS
-
Provided herein are compounds of the Formula I: and pharmaceutically acceptable salts, solvates and polymorphs thereof, wherein L, X1, R1, R2, R3, R4, R5 and R6 are as defined herein, for the treatment of BRAF-associated diseases and disorders, including BRAF-associated tumors, including malignant and benign BRAF-associated tumors of the CNS and malignant extracranial BRAF-associated tumors.
- -
-
Paragraph 0973; 0974
(2021/01/20)
-
- QUINAZOLINEDIONES AS TANKYRASE INHIBITORS
-
This invention relates to the use of quinazolinediones for the modulation, notably the inhibition of the activity of tankyrases (TNKS1 and TNKS2). Suitably, the present invention relates to the use of quinazolinediones in the treatment of cancer, fibrosis and other hyperproliferative diseases through this mechanism.
- -
-
Page/Page column 51
(2014/01/07)
-