Stereoselective synthesis of azetidine-derived glutamate and aspartate analogues from chiral azetidin-3-ones
The stereoselective syntheses of cis conformationally constrained glutamate and aspartate analogues, containing an azetidine framework were accomplished from (S)-N-tosyl-2-phenylglycine in moderate overall yields. The key steps in these syntheses involved
Burtoloso, Antonio Carlos B.,Correia, Carlos Roque D.