- Changes to the triaxial composition of the hydrated phases (CaO/Al 2O3/SiO2) in the metakaolin/lime system
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This study examines the composition of certain hydrates (calcium silicate, aluminum silicate, and related phases) produced by the pozzolanic reaction of waste-paper sludge that had previously been activated at different temperatures. It summarizes and compares the evolution of the oxide compounds, and records their stability intervals. Changes to their mineralogical composition were analyzed using X-Ray Diffraction, scanning electron microscopy, and energy dispersive X-ray spectroscopy. The hydration products from 1 to 360 days of curing time were CSH gels, hydrotalcite-type compounds (LDH), and stratlingite (C2ASH8). CSH gels were employed as substrates for growing other materials and their morphologies were modified from fibrous to hexagonal layers. The composition of the LDH-type compounds observed in the carbonate group varied with changes in curing time. Two LDH-type compound types were identified: (a) with and (b) without magnesium. Stratlingite was the only stable material after long-curing times.
- Garcia Gimenez, Rosario,Rodriguez, Olga,Vigil De La Villa, Raquel,Frias, Moises
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- Studies of the Rate of the Formation of Talc under Hydrothermal Conditions at 400-460 deg C
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The rate of the formation of talc from brucite powders with soluble silica under hydrothermal conditions was investigated in the temperature range of 400-460 deg C, a range including the equilibrium temperature for the reaction: brucite+serpentine2forsterite+3H2O.Serpentine appeared as an intermediate phase below 415 deg C, while above 430 deg C forsterite appeared in addition to serpentine.The apparent reaction can be represented as:(below 415 deg C) brucite-->serpentine-->talc; (above 430 deg C) brucite-->serpentine(forsterite)-->talc; brucite-->forsterite(serpentine)-->talc The reaction was apparently expressed as a pseudo-first-order reaction.The overall rate of the reaction did not increase with the increase in the temperature.Arrhenius plots of the rate constants for the overall reaction showed a curve with a maximum at about 415 deg C and a minimum at about 445 deg C which was caused by the alteration of the reaction by the appearance of forsterite at 430 deg C.
- Muraishi, Haruto
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- REACTION OF MAGNESIUM HYDROXIDE WITH SOLUBLE SILICA UNDER HYDROTHERMAL CONDITIONS BELOW THE CRITICAL TEMPERATURE.
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The mechanism of the synthetic reaction of silicates under hydrothermal conditions is of interest, but it has not been investigated except for the syntheses of zeolite below 100 degree C. The purpose of this study is to gain some insight into the mechanis
- Muraishi
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- Synthesis of magnesium silicate by heat treatment of sols and mechanical activation of solid components
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A layered magnesium silicate, an analog to natural talc, was synthesized by mechanical treatment of a mixture of magnesium hydroxide and hydrated silicic acid powders, as well as by heat treatment of aqueous dispersions containing magnesium hydroxide particles and silica sols prepared from different precursors.
- Dudkin,Vasyutin
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p. 751 - 755
(2011/09/14)
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- Pharmaceutical composition comprising N-[2-(Diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene) methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
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The present invention relates to a pharmaceutical composition comprising N-[2-(diethylamino)ethyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1 H-pyrrole-3-carboxamide as active pharmaceutical ingredient.
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- ANTIPSYCHOTIC BENZOTHIOPYRANYLAMINES
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Disclosed are 3,4-dihydro-2H-1-benzothiopyran-3-yl-methyl-and ethylamines useful as antipsychotics, processes for the preparation of said compounds, pharmaceutical compositions containing same, and a method of treating psychotic disorders by administering said compounds.
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- Novel alpha-cyano-beta-oxopropionamides
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α-(Substituted carbamoyl)-β-aryl- and heteroaryl-β-oxo-propionitriles of formula, , A-CO- enol ethers thereof and salts thereof, as well as pharmaceutical preparations containing same and methods of preparing and using these compounds are disclosed. Said compounds represent novel antiinflammatory and antirheumatic agents. Their property to interfere with both the cyclooxygenase and lipoxygenase pathway of the arachidonic fatty acid bioconversion to inflammatory mediators make them valuable therapeutics. These properties render the mentioned substituted carbamoyl-β-oxopropionitriles useful for the treatment of arthritic and rheumatic diseases and other inflammatory conditions in mammals.
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- Solid, stable dosage forms with an elastic film coating
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Solid, stable dosage forms consisting of a moisture- and temperature-sensitive core prepared from a medicament, or a mixture of medicaments, and excipients, and an elastic film coating which decomposes in aqueous solution, said elastic film coating substantially comprising (a) a water-soluble component consisting of 20-60% of hydroxypropyl cellulose having an average molecular weight of 75,000, and (b) a water-insoluble component consisting of 5-20% of an acrylic resin in the form of (b1) a 70:30 ethyl acrylate/methyl methacrylate copolymer having a molecular weight of 80,000, or (b2) a 30:70 to 70:30 methyl acrylate/methyl methacrylate copolymer having an average molecular weight of 500,000, 20-60% of a lubricant, 0.5-5% of a wetting agent, 0-5% of a plasticizer, and optional additional excipients, and process for the preparation thereof.
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- Cosmetic composition, particularly for decorative applications
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The invention relates to a cosmetic composition, particularly for decorative applications, with a proportional content of a liquid, highly viscous or solid, dermatologically compatible carrier material and a pure powder of precious stones or precious stone mixtures.
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- Process for inhibiting blood platelet aggregation and promoting vasodilation
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A method for inhibiting blood platelet aggregation in humans, and promoting vasodilation in humans, by administering to a human in need of the same an effective amount of 2-hydroxy-3-isopropyl-5,6-dimethylpyrazine or a hydrate or a pharmaceutically acceptable non-toxic salt thereof. Administration can be orally in an amount of about 0.02-12 mg/kg body weight per day, or parenterally in an amount of about 0.01-6 mg/kg of body weight per day.
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- Use of 2-aminoalkyl-5-pyridinols as nootropic agents and antidepressants
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The present invention relates to the use of secondary 2-aminoalkyl-5-pyridinols of the general formula I STR1 wherein R is hydrogen or lower alkyl, m is an integer from 2 to 4 and n is an integer from 1 to 7, and the acid addition salts thereof, as nootropic agents and antidepressants and for the preparation of pharmaceutical compositions having nootropic and antidepressant activity.
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- Certain β-oxo-α-carbamoylpyrrolepropionitriles
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1-Unsubstituted β-oxo-α-(phenylcarbamoyl)-β-pyrrolylpropionitriles, e.g. those of the formula STR1 wherein R1 and R2 =H or alkyl, and R3 and R4 =H, alkyl, alkoxy, OH, halogen or CF3, are analgesic, and antiarthritic agents. Their synthesis, pharmaceutical compositions thereof, and methods of treatment utilizing such compounds are included.
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- 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
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Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-ones and functional derivatives are angiotensin converting enzyme inhibitors and are useful as antihypertensive agents. Synthesis of, compositions and methods of treatment utilizing such compounds are included.
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- 3-Substituted-2-(heteroaryl) indoles
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Disclosed as thromboxane synthetase inhibitors are the compounds of formula STR1 wherein R1 represents hydrogen or lower alkyl; Ar represents 3-pyridyl or 1-imidazolyl, each unsubstituted or substituted by lower alkyl, carboxy, lower alkoxycarbonyl or carbamoyl; R2 and R3 independently represent hydrogen, lower alkyl, halogen, trifluoromethyl, hydroxy, lower alkoxy, carboxy lower alkyl, lower alkoxycarbonyl lower alkyl, carboxy, lower alkoxycarbonyl, or lower alkyl-(thio, sulfinyl or sulfonyl), or R2 and R3 together on adjacent carbon atoms represent lower alkylenedioxy; A represents straight chain or branched alkylene of 3 to 12 carbon atoms in which the number of the carbon atoms separating the indole nucleus from group B is 3 to 12, straight chain or branched alkenylene of 2 to 12 carbon atoms, straight chain or branched alkynylene of 2 to 12 carbon atoms, lower alkylenephenylene-lower (alkylene or alkenylene), lower alkylenephenylene, lower alkylene-(thio or oxy)-lower alkylene, lower alkylene-(thio or oxy)-phenylene, or lower alkylene-phenylene-(thio or oxy)-lower alkylene; B represents carboxy, esterified carboxy, carbamoyl, mono- or di-lower alkylcarbamoyl, hydroxymethyl, cyano, hydroxycarbamoyl, 5-tetrazolyl or formyl; the imidazolyl and pyridyl N-oxide thereof; or a pharmaceutically acceptable salt thereof; as well as their synthesis, pharmaceutical compositions thereof, and methods of treatment utilizing such compounds.
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- Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment
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Carbamoyl derivatives of 4,5,6,7-Tetrahydroisoxazolo[5,4-c] Pyridine-3-one, and method of preparation, pharmaceutical compositions thereof, and methods of treatment of GABA-system malfunctions therewith, are all disclosed.
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- Dilignols and dilignol-type compounds
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Compounds of formula STR1 wherein at least one of R5 or R6 bears a substituted amino group, are useful as liver protecting agents.
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- Alicyclic amides having a physiological cooling effect
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Alkyl-substituted alicyclic carboxylic acids, esters and amides are disclosed having the property of stimulating the cold receptors of the nervous system of the human body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations.
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- 2-Methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene and salts thereof, neuroleptic compositions and method of use
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The present invention relates to the novel compound 2-methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene of the formula STR1 and its non-toxic acid addition salts, which compounds have strong and longlasting neuroleptic properties and, at the same time, a low degree of undesired side effects such as extrapyrimidal side effects. The invention moreover relates to a method for the preparation of said novel compounds, pharmaceutical compositions containing same, which may be administered to animals, including human beings, orally or parentally. Further the invention relates to a method for producing an antipsychotic effect in warmblooded animals by administering to said animals an antipsychotically effective amount of one of said novel compounds.
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- P-Menthane carboxamides having a physiological cooling effect
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N-substituted-p-menthane-3-carboxamides are disclosed having the property of stimulating the cold receptors of the nervous system of the human body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations.
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- Compositions having a physiological cooling effect
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Alkyl-substituted methanols are disclosed having the property of stimulating the cold receptors of the nervous system of the human body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations.
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- Compounds having a physiological cooling effect, and compositions containing them
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Cyclic and acyclic amides, substituted ureas and sulphonamides are disclosed having the property of stimulating the cold receptors of the nervous system of the human body to produce a cold sensation and are used for this purpose in a variety of edible and topical preparations and in tobacco.
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