cas 149981-36-2, Benzamide, N-(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)-4-(trifluoromethyl)- | Articles data ｜lookchem

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149981-36-2

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Effect of Trifluoromethyl and Other Substituents on Activity of Xanthines at Adenosine Receptors
An aryl p-(trifluoromethyl) substituent increases the affinity of 1,3-disubstituted 8-phenylxanthines at A2a-adenosine receptors, while having little effect on affinity at A1-adenosine receptors.In contrast, an aryl p-(trifluoromethy
Jacobson, Kenneth A.,Shi, Dan,Gallo-Rodriguez, Carola,Manning, Malcolm,Mueller, Christa,et al.
p. 2639 - 2644
(1993)
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149981-17-9
8-<4-(trifluoromethyl)phenyl>-1,3-di-n-propylxanthine

Chemical Properties

Density: 1.37±0.1 g/cm3(Predicted)
PKA: 10.77±0.20(Predicted)
PSA: 99.12000
LogP: 3.33750

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