A one-pot procedure has been proposed for the synthesis of amines directly from cage hydrocarbons. A number of cage amines have been synthesized by treatment of adamantane, its homologs, and structurally related cage hydrocarbons with nitric acid in acetic acid and subsequent addition of urea and heating.
Leonova,Skomorokhov,Moiseev,Klimochkin
p. 1703 - 1709
(2016/02/03)
PROCESS FOR PREPARING MEMANTINE HYDROCHLORIDE SUBSTANTIALLY FREE OF IMPURITIES
The present invention encompasses processes for preparing Memantine hydrochloride and its derivatives, substantially free of impurities.
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Page/Page column 22-23
(2008/06/13)
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