TANDEM GENERATION AND INTRAMOLECULAR TRAPPING OF CHIRAL STABILISED AZOMETHINE YLIDS WITH ALKYNE DIPOLAROPHILES
Due to steric contraints imposed upon the bridging chain by the three-carbon linear unit associated with the alkyne, hex-5-ynal condenses with (5R)-phenylmorpholin-2-one (1) and undergoes intramolecular 3+2 dipolar cycloaddition via the syn-azomethine yli