Synthesis of the First Thienothiophene Stabilized Only by Electronic Effects
The stable, crystalline 1,3-dibromo-4,6-dicyanothienothiophene (3a) has been synthesized.This is the first example of a thienothiophene stabilized solely by electronic effects.The dicarbomethoxy dibromo analog 3b and the tetrabromo analog 3c were also generated and found to be considerably less stable.
Synthesis and biological evaluation of novel benzimidazole derivatives and their binding behavior with bovine serum albumin
A series of novel benzimidazole derivatives were synthesized and characterized by 1H NMR, 13C NMR, MS, IR and HRMS spectra. All the new compounds were screened for their antimicrobial activities in vitro by two-fold serial dilution t