- On the search for potential anti-Trypanosoma cruzi drugs: Synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions
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Five 2-hydroxy-3-substituted-aminomethyl naphthoquinones, nine 1,2,3-triazolic para-naphthoquinones, five nor-β-lapachone-based 1,2,3-triazoles, and several other naphthoquinonoid compounds were synthesized and evaluated against the infective bloodstream
- Da Silva Jr., Eufranio N.,De Melo, Isadora M.M.,Diogo, Emilay B.T.,Costa, Verenice A.,De Souza Filho, José D.,Valen?a, Wagner O.,Camara, Celso A.,De Oliveira, Ronaldo N.,De Araujo, Alexandre S.,Emery, Flávio S.,Dos Santos, Marcelo R.,De Simone, Carlos A.,Menna-Barreto, Rubem F.S.,De Castro, Solange L.
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experimental part
p. 304 - 312
(2012/07/27)
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