- Synthesis of Barbaralones and Bullvalenes Made Easy by Gold Catalysis
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The gold(I)-catalyzed oxidative cyclization of 7-ethynyl-1,3,5-cycloheptatrienes gives 1-substituted barbaralones in a general manner, which simplifies the access to other fluxional molecules. As an example, we report the shortest syntheses of bullvalene, phenylbullvalene, and disubstituted bullvalenes, and a readily accessible route to complex cage-type structures by further gold(I)-catalyzed reactions.
- Ferrer, Sofia,Echavarren, Antonio M.
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p. 11178 - 11182
(2016/10/13)
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