A new class of oxygen nucleophiles for regioselective 1,4-addition to butadiene monoxide catalyzed by palladium complexes
Butadiene monoxide reacts with high regioselectively with anhydrides to give preferentially diesters of 2 buten-1,4-diol in presence of palladium phosphine complexes. Reaction regioselectivity is strongly influenced by the nature of palladium ligand, anhydride and solvent.