The invention relates to a 1,3-indandione sodium salt preparation method, which specifically comprises the following steps: reacting a phenyl grignard reagent with lactate to produce 1,1-substituted diphenyl-1,2-propanediol, namely an intermediate 1; dehy
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(2018/04/02)
Palladium-catalyzed amination of aromatic C-H bonds with oxime esters
"Chemical equation presented" We report a conceptually new approach to the direct amination of aromatic C-H bonds. In this process, an oxime ester function reacts with an aromatic C-H bond under redox-neutral conditions to form, in the case studied, an indole product. These reactions occur with relatively low catalyst loading (1 mol %) by a mechanism that appears to involve an unusual initial oxidative addition of an N-O bond to a Pd(0) species. The Pd(II) complex from oxidative addition of the N-X bond has been isolated for the first time, and evidence for the intermediacy of such oxidative addition products in the catalytic reaction has been gained.
Tan, Yichen,Hartwig, John F.
supporting information; experimental part
p. 3676 - 3677
(2010/05/15)
Novel synthesis of α-arylnaphthalenes from diphenylacetaldehydes and 1,1-diphenylacetones
A two-step synthesis of 1-amino-4-arylnaphthalene-2-carbonitriles from diphenylacetaldehydes and 1,1-diphenylacetones involves condensation of the carbonyl compounds with malonodinitrile and cyclization of the aryl-ylidenemalonodinitriles obtained in conc
Kozik, Bart?omiej,Wilamowski, Jaros?aw,Góra, Maciej,Sepio?, Janusz J.
p. 3435 - 3438
(2007/10/03)
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