- Hydrogen peroxide responsive compound for imaging and therapy and synthetic method thereof
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The invention discloses a hydrogen peroxide responsive compound for imaging and therapy and a synthetic method thereof. The chemical structure of the responsive compound is shown in the following figure defined in the specification. The invention also pro
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Paragraph 0091-0093
(2020/09/16)
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- An optimised procedure for PTFE phase vanishing reactions: An improved reaction design and the use of reagents adsorbed on silica
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While the phase-vanishing (PV)-PTFE reaction design works well with a broad range of substrates and reaction conditions, there are occasional problems. A description of the problems and their importance, including their effects on the reaction outcome and ways to address them, are discussed. Details of an improved design, a hybrid of previously reported PV-PTFE and solvent-free PV-PTFE designs, is presented, as well as the use of silica-supported reagents.
- Parsons, Brendon A.,Smith, Olivia Lin,Dragojlovic, Veljko
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p. 574 - 581
(2015/11/27)
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- The Hammett correlation between distyrylbenzene substituents and chemiluminescence efficiency providing various ρ-values for peroxyoxalate chemiluminescence of several oxalates
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Peroxyoxalate chemiluminescence (PO-CL) was investigated using eight oxalates with various phenol moieties and the distyrylbenzene (DSB) fluorophores with various substituents. The ρ-values in the Hammett correlation between the substituent constants (σp+) of the DSBs and the singlet chemiexcitation yields (ΦS) for the PO-CL reactions varied from -0.50 to -1.01 depending on the oxalate structure, and the reactive oxalates tended to afford the higher absolute ρ-values but with a few exceptions. Based on the CIEEL mechanism, these experimental observations suggest that the aryloxy groups still remain in the 1,2-dioxetanones (DOTs), which are the postulated high-energy intermediates, and control the electronic properties of DOTs as electron-acceptors. The LUMO energies of the DOTs calculated by the ab initio method with a B3LYP/6-31g(d) basis set reveal that the lower the DOT-LUMO energies, the higher the absolute ρ-values were provided for the corresponding oxalates, as predicted by the frontier molecular orbital (FMO) theory. Thus, the chemical species interacting with the DSBs would be not unitary and will be DOTs.
- Maruyama, Takayuki,Narita, Susumu,Motoyoshiya, Jiro
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p. 222 - 231
(2013/03/13)
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