- Synthesis and spectral studies of 4,4′-(Hydrazine-1,2-diylidenedimethylylidene)-bis-(2-methoxyphenol) and its transition metal complexes with promising biological activities
-
The study describes the synthesis, characterization and biological activity of a novel Schiff base ligand and its transition metal complexes. The Schiff base ligand was obtained by a condensation reaction between 4-hydroxy-3-methoxybenzaldehyde (p-vanilli
- Rani, Anita,Kumar, Manoj,Tuli, Hardeep Singh,Abbas, Zahoor,Prakash, Vinit
-
-
Read Online
- Dihydrazone-based dynamic covalent epoxy networks with high creep resistance, controlled degradability, and intrinsic antibacterial properties from bioresources
-
Covalent adaptable networks (CANs) provide a promising approach to solve the issue of recycling thermosets due to their dynamic cross-linked networks. However, CANs are susceptible to creep at relatively low temperatures, and their chemical stability is also inevitably doubtful. Here, we designed novel dihydrazone CANs by cross-linking a dihydrazone-containing epoxy monomer, which was synthesized from the condensation of a lignin derivative vanillin and hydrazinium hydrate, followed by a reaction with epichlorohydrin. Besides the excellent malleability and reprocessability, the dihydrazone CANs exhibited a high initial creep temperature of ～105 °C, which was ascribed to the superior stability of the hydrazone bond at around 100 °C and favorable hydrazone exchangeability at elevated temperatures. Meanwhile, the degradation of the dihydrazone CANs exhibited temperature, solvent, and acidity dependence. Moreover, on account of the high antibacterial properties of the hydrazone bond, the CANs presented a high killing rate (95.8%) for Gram-negative bacteria (E. coli). Thus, this work discloses an effective dynamic covalent motif for the development of CANs with excellent dimensional stability, chemical resistance, and intrinsic antibacterial properties.
- Feng, Jie,Li, Qiong,Liu, Yanlin,Lu, Na,Ma, Songqi,Wang, Sheng,Wu, Jiahui,Xu, Xiwei,Yang, Jintao,Zhu, Jin
-
p. 11261 - 11274
(2020/06/17)
-
- 1,5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies
-
Herein, we report the design and synthesis of 13 diarylpyrazole hybrids with vanillin constructed as dual compounds against oxidative stress and diabetes. Compounds were tested in two different antioxidant assays. It was found that all compounds showed an
- Hernández-Vázquez, Eduardo,Casta?eda-Arriaga, Romina,Ramírez-Espinosa, Juan José,Medina-Campos, Omar Noel,Hernández-Luis, Francisco,Chaverri, José Pedraza,Estrada-Soto, Samuel
-
p. 106 - 118
(2015/06/22)
-
- CONDENSATION OF p-(DIMETHYLAMINO)BENZALDEHYDE WITH HYDRAZINE IN A MICELLAR MEDIUM
-
The rate of the condensation of p-(dimethylamino)benzaldehyde with hydrazine in aqueous solution and the yield of the product (the amine) rise by two orders of magnitude in presence of micelles of sodium dodecyl sulfate.It was found that the micellar effect in the kinetics is manifested at the first dimolecular stage of the reaction of the aldehyde with hydrazine and is explained by the concentrating of the reactants in the micelles.The rate constants of the condensation of hydrazine with a number of substituted benzaldehydes conform to the Hammett equation with a low positive value of ρ.
- Yatsimirskii, A. K.,Yatsimirskaya, N. T.,Krivova, S. B.
-
p. 752 - 757
(2007/10/02)
-
