The present invention provides a method of synthesizing an intramolecularly bridged polypeptide comprising at least one intramolecular bridge. The present invention further provides a method of synthesizing an intramolecularly bridged polypeptide comprisi
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Page/Page column 12; Figure 6
(2008/06/13)
An appraisal of new variants of Dde amine protecting group for solid phase peptide synthesis
A series of new variants of Dde, substituted at the exocyclic alkene position have been developed and their application in solid phase peptide synthesis assessed. The new derivatives offer complete resistance towards 20% piperidine in DMF and provide a considerable barrier towards N→N'-intramolecular migration.
Chhabra, Siri Ram,Hothi, Bhupinder,Evans, David J.,White, Peter D.,Bycroft, Barrie W.,Chan, Weng C.
p. 1603 - 1606
(2007/10/03)
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