Synthesis of ketone O-allyloximes and O-propargyloximes in KOH-DMSO system
In reaction of ketone oximes with allyl bromide and propargyl chloride in KOH - DMSO system were obtained in good yield previously unknown ketone O-allyloximes and O-propargyloximes. The reactions are accompanied with minor regeneration of ketones (up to 12%, mainly 1-5%).
The Base-Catalysed Rearrangement of O-Propargyl Ketoximes to N-1-Alkenyl Acryl Amides
O-Propargyl ketoximes, available from the reaction of ketoximes with propargyl halides in KOH/DMSO system, readily undergo base-catalysed (t-BuOK in DMSO or THF) rearrangement to N-(1-alkenyl)acrylamides in 15-58percent yields.
Trofimov, Boris A.,Tarasova, Ol'ga A.,Sigalov, Mark V.,Mikhaleva, Al'bina I.
p. 9181 - 9184
(2007/10/02)
More Articles about upstream products of 174004-17-2