Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug
Chagas disease chemotherapy, currently based on only two drugs, nifurtimox and benznidazole, is far from satisfactory and therefore the development of new antichagasic compounds remains an important goal. On the basis of antichagasic properties previously
Vega, María Celeste,Rolón, Miriam,Montero-Torres, Alina,Fonseca-Berzal, Cristina,Escario, José Antonio,Gómez-Barrio, Alicia,Gálvez, Jorge,Marrero-Ponce, Yovani,Arán, Vicente J.
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Hypolipidemic Activity of Phthalimide Derivatives. 7. Structure-Activity Studies of Indazolone Analogues
The apparent benefit of limiting serum cholesterol and triglyceride levels either by dietary restriction or drug therapy has prompted work in our laboratories toward development of a suitable antihyperlipidemic agent.We have demonstrated the antihyperlipi
Wyrick, Steven D.,Voorstad, P. Josee,Cocolas, George,Hall, Iris H.
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(2007/10/02)
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