Isomerization of 4-aminobenzofurans to 4-hydroxyindoles
4-Amino-2-methylbenzofurans are quantitatively converted to 4-hydroxy- 2-methylindoles in acidic medium. The rearrangement mechanism involves the ring opening of the furan ring to produce an intermediate carbocation, which undergoes ring clo- sure to the
Chilin,Rodighiero,Guiotto
p. 309 - 312
(2007/10/03)
Synthesis of methyl derivatives of 4H-furo[2,3-h]quinolin-4-one and 5H-furo[3,2-g]quinolin-5-one
Synthesis of the linear and angular furoquinolin-4-one derivatives 6 and 12 was performed, using nitrobenzofurans 3 and 9 as key intermediates. These compounds were reduced to the corresponding aminobenzofurans 4 and 10, which were condensed in two steps