From tyrosine to glycine: Synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor
The characterization of the native and recombinant P2X7 receptor continues to be hindered by the lack of specific and subtype-selective antagonists with a "druglike" profile. However, a tyrosine derivative named KN-62 exhibits selective P2Xsub
Romagnoli, Romeo,Baraldi, Pier Giovanni,Carrion, Maria Dora,Cara, Carlota Lopez,Preti, Delia,Cruz-Lopez, Olga,Tabrizi, Mojgan Aghazadeh,Moorman, Allan R.,Gessi, Stefania,Fogli, Eleonora,Sacchetto, Valeria,Borea, Pier Andrea
p. 3706 - 3715
(2008/02/09)
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