Pyrido[1,2-a]pyrimidin-4-ones as antiplasmodial falcipain-2 inhibitors
Plasmodium falciparum cysteine protease falcipain-2 (FP-2) is a promising target for antimalarial chemotherapy and inhibition of this protease affects the growth of parasite adversely. A series of pyrido[1,2-a]pyrimidin-4-ones were synthesized and evaluat
Mane,Li,Huang,Gupta,Nadkarni,Giridhar,Naik,Yadav
p. 6296 - 6304
(2012/11/13)
Limitations of the Jacobs-Gould reaction using microwave irradiation
Upon investigating the green synthesis of some antimicrobial quinolone compounds, some atypical ring-closing patterns were observed during the synthesis of various intermediates using the Jacobs-Gould reaction.
Smith, Robert B.,Faki, Hajira,Leslie, Ray
experimental part
p. 1492 - 1499
(2011/06/17)
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