A pyrimidine compound represented by below formula (I) has excellent control activity against pests and is useful as an active ingredient of a pest controlling agent.
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Page/Page column 148; 149
(2010/12/18)
THIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS
The invention encompasses compounds of Formula I (I) or pharmaceutically acceptable salts thereof, which are antagonist of the CXCR3 chemokine receptor useful for the treatment or prevention of pathogenic inflammatory processes, autoimmune diseases or graft rejection processes. Methods of use and pharmaceutical compositions are also encompassed.
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Page/Page column 73
(2008/06/13)
Substituted AZA- and diazacycloheptane and -cyclooctane
Aza- and diazacyclohexane and -cyclooctane compounds of the following formula: Ar1—A—B—Ar2??(I) where Ar1, A, B and Ar2have the meanings stated in the description have a high affinity for the dopamine D3/s
The fumaric acid salt of 2-{3-[4-(2-t-butyl-6-trifluoromethyl-4-pyrimidinyl)-1-piperazinyl]propylthio}-4-pyrimidinol is useful for treating disorders which respond to dopamine D3 ligands. It has higher stability at low pH and is therefore particularly suitable for oral administration in pharmaceutical compositions comprising this salt.
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(2008/06/13)
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