The first general synthesis of N-substituted 1,2-benzisoxazolin-3-ones
A convenient synthesis of the title compounds has been developed. Key synthetic steps include: (1) conversion of the readily available salicylic acid derivatives to the corresponding N-substituted salicylhydroxamic acids; (2) cyclization of the hydroxamic acids under Mitsunobu conditions to give the title compounds. (C) 2000 Elsevier Science Ltd.
Shi, Guo-Qiang
p. 2295 - 2298
(2007/10/03)
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