cas 19752-09-1, 3,4-DICHLOROBENZYL ISOCYANATE | Articles data ｜lookchem

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19752-09-1

Articles about 19752-09-1Total 4 be found

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Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity, wherein X1, X2, X3, X4, X5, R5, R6, R7, R8a, R8b, R9, Z1, Z2 and L are as defined in the description.
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(2008/06/13)

Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.
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Page/Page column 52

(2010/02/11)

Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.
-
(2008/06/13)

Synthesis, selective aldose reductase inhibitory profile and antihyperglycaemic potential of certain parabanic acid derivatives
Synthesis and aldose reductase inhibitory profile of certain parabanic acid derivatives 1a-p is described. Also, the antihyperglycaemic potential of these compounds was studied. The most active inhibitors in this series were compounds 1 g, 1p, and 1o which showed inhibitory activity, 36.6, 90 and 91% respectively, at concentration 1 × 10-4. Their IC50 were 2 × 10-6, 7.5 × 10-8 and 5 × 10-8, respectively. Compound 1o exhibited pronounced antihyperglycaemic effect.
Nabil Aboul-Enein,El-Azzounya,Maklad,Attia,Wiese
p. 329 - 350
(2007/10/03)

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Chemical Properties

Appearance/Colour :clear colourless slightly viscous liquid
Boiling Point: 271.31 °C at 760 mmHg
Flash Point:101.814 °C
Density: 1.317 g/cm³
Storage Temp.:?20°C
Vapor Pressure: 0.0065mmHg at 25°C
Refractive Index: n20/D 1.568(lit.)
PSA: 29.43000
LogP: 2.82920

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