- Novel pyrrolidine or piperidine derivatives having activity for T-type calcium channel
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A pyrrolidine or piperidine compound having activity for T - type calcium channel, wherein the pyrrolidine or piperidine compound of Formula 1 according to the present invention has an excellent antagonistic activity to, T-type calcium channel, and can be used as a preventive or therapeutic agent, for pain diseases, or cancer related to cancer, or cancer such as, epilepsy and,hepatic pain, angina. (by machine translation)
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Paragraph 0389-0392; 0404-0407
(2020/04/23)
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- FATTY ACID SYNTHASE INHIBITORS
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This invention relates to carboxamides and reverse carboxamides according to Formula (I) and the use of carboxamides and reverse carboxamides for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of carboxamides and reverse carboxamides in the treatment of cancer.
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- FATTY ACID SYNTHASE INHIBITORS
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This invention relates to the use of imidazole, triazole, and tetrazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of imidazoles, triazoles, and tetrazoles in the treatment of cancer.
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- BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS
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This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of benzimidazoles in the treatment of cancer.
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- AZABENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS
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This invention relates to the use of azabenzimidazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of azabenzimidazoles in the treatment of cancer.
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- Pyrrolidine derivatives-CCR-3 receptor antagonists
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This invention relates to certain 3-aminomethylpyrrolidine derivatives of Formula (I): that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.
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- 1-methylcarbapenem derivatives
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A 1-methylcarbapenem compound represented by the following formula: STR1 [wherein R1 represents a hydrogen atom or a lower alkyl group, R2 represents a hydrogen atom or a lower alkyl group, R3 represents a hydrogen atom, a
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