- Antibacterial activity of coumarine derivatives synthesized from 4-Chloro-chromen-2-one. The comparison with standard drug
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This work reports the synthesis of some new derivatives from 4-Chloro-chromen-2-one and describe the results of antibacterial activity of purified compounds. Compounds 4-Butylamino-chromen-2-one (1a) , 4-Butylamino-2-oxo-2H-chromene-3-sulfonyl chloride (2
- Behrami, Aziz
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- Synthesis and Photophysical Properties of 1,4-Dihydro-2 H,5H-chromeno[4,3-D][1,3]oxazin-5-ones, and Derivatives Containing Tethered 1,2,3-Triazoles, from 4-Aminocoumarins
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A facile protocol for the unprecedented one-pot H 2 SO 4 -mediated hydroxymethylation/cyclative N, O -acetalization of 4-aminocoumarins to 1,4-dihydro-2 H,5 H -chromeno[4,3- d ][1,3]oxazin-5-ones, in moderate to good yields, was deve
- Brites, Nathan P.,Dilelio, Marina C.,Iglesias, Bernardo A.,Kaufman, Teodoro S.,Silveira, Claudio C.,Vieira, Larissa A.
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p. 2965 - 2976
(2019/07/22)
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- A regioselective synthesis of pentacyclic compounds containing coumarin, pyrrole, indene without catalysts under microwave irradiation
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A concise and efficient approach was developed for the synthesis of pentacyclic compounds containing coumarin, pyrrole, indene in a regioselective manner in good yields via the reactions of N-substituted 4-aminocoumarin compounds and ninhydrin using micro
- Chen, Zhi-Wei,Hou, Jun-Bo,Dai, Zhao-Ran,Yang, Xiao-Feng
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supporting information
p. 1622 - 1625
(2016/10/30)
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- A convenient approach to the synthesis of dialkyl 5-oxo-1,2-dihydro-5H- chromeno [4,3-b]pyridine-2,3-dicarboxylates
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Coumarin and its analogs are considered privileged scaffolds in the current synthetic and pharmacological research. The chemical behavior of enaminocarbaldehydes of the coumarin moiety under intramolecular Wittig reaction conditions in the presence of tri
- Glasnov, Toma N.,Ivanov, Ivo C.
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p. 1579 - 1588
(2008/09/20)
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- SYNTHESIS AND STUDY OF THE PROPERTIES OF 4-SUBSTITUTED 3-AMINOMETHYLCOUMARINS
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The aminomethylation of 4-hydroxycoumarin gave 3-pyrrolidinomethyl- and 3-piperidinomethyl-4-hydroxycoumarins, which were converted to 4-chloro derivatives by the action of phosphorus oxychloride.A number of 3-pyrrolidinomethyl- and 3-piperidinomethyl-4-aminocoumarins were synthesized by reaction of the 4-chloro derivatives with various amines, and some of their properties were studied.
- Savel'ev, V. L.,Artamonova, O. S.,Troitskaya, V. S.,Shaviryna, V. V.,Afanas'eva, T. G.,Zagorevskii, V. A.
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p. 676 - 679
(2007/10/02)
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