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226700-79-4

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Methods for predicting the response to statins
The invention provides methods for optimizing therapeutic efficacy for treating hypercholesterolemia in a subject having a cardiovascular disease (CVD), comprising (a) determining subject characteristics that affect the likelihood of reaching a goal level of low density lipoprotein (LDL); and (b) obtaining success probabilities of a variety of statin treatments for reaching said goal level of LDL using said subject characteristics and a multivariate model; and (c) administrating the optimal statin treatment with the highest success probability of step (b) to said subject thereby optimizing therapeutic efficacy for treating hypercholesterolemia in said subject.
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(2011/10/13)

PREPARATION OF FOSAMPRENAVIR CALCIUM
Process for preparation of fosamprenavir and its intermediate salts using novel phthalimide intermediates.
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Page/Page column 7-8

(2011/10/04)

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Chemical Properties

Density: 1.4 g/cm³
Refractive Index: 1.611
PKA: 1.77±0.10(Predicted)
PSA: 195.91000
LogP: 4.57270

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