Disclosed are substituted thioimidazolidinone compounds and pharmaceutical compositions comprising such compounds. The compounds and compositions can be used for treatment of androgen receptor-associated diseases or disorders, such as prostate cancer, benign prostatic hypertrophy, male hair loss and hypertrichosis.
Compounds of the formula: STR1 where R is hydrogen or A--(CF2)m --CH2 --; A is --F or --H; n is an integer from 1 to 10, inclusive; m is an integer from 0 to 9, inclusive; p is an integer from 0 to 4, inclusive; and Y is h
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(2008/06/13)
Synthesis of 4-Arylbutanenitriles
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Sanchez, Ignacio H.,Aguilar, Maria Antonieta
p. 55 - 56
(2007/10/02)
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