cas 23583-48-4, 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
23583-48-4

Articles about 23583-48-4Total 5 be found

Article title
Article abstract
Author
Journal number and time
Download

-
-
Chu et al.
p. 406
(1974)
Read Online

-
-
Myasoedov et al.
(1979)
Read Online

PROCESS FOR THE PREPARATION OF AN (RP)-8-SUBSTITUTED CAMPS
This invention relates to a process for the preparation of an (Rp)-8-substituted adenosine-3',5'-cyclic phosphorothioic acid, or a salt or ester thereof, which comprises P-amidating 8-bromoadenosine-3',5'-cyclic phosphoric acid, and reacting the P-amidate with a base and with carbon disulphide to yield (Rp)-8-bromoadenosine-3',5'-cyclic phosphorothioic acid or a salt or ester thereof.
-
Page/Page column 8-9; 12

(2008/06/13)

Stereoselective preparation of (RP)-8-hetaryladenosine-3′, 5′-cyclic phosphorothioic acids
Cyclic adenosine monophosphate (cAMP) has been converted into its 8-bromo derivative and 2′O-TBDMS protected before activation of the phosphoric acid moiety with a reagent generated in situ from oxalyl chloride and DMF. Further reactions with primary amines furnished corresponding phosphoramidates with high stereoselectivity at the phosphorus atom. Cross-coupling reactions with the 8-bromopurine yielded 8-hetaryl derivatives. X-Ray analyses showed the amidates to possess the (SP)-configuration. Carbon disulfide effected thiylation under strongly basic conditions stereospecifically provided the (RP)-phosphorothioic acids. The Royal Society of Chemistry.
Andrei, Mioara,Bjornstad, Vidar,Langli, Geir,Romming, Christian,Klaveness, Jo,Tasken, Kjetil,Undheim, Kjell
p. 2070 - 2080
(2008/03/12)

PURINE NUCLEOTIDE DERIVATIVES
This invention provides novel 8-carbyl substituted cAMPS and a novel procedures for the preparation of 8-Br-cAMP, a key starting material.
-
Page/Page column 64

(2010/02/15)

Coumarinylmethyl esters for ultrafast release of high concentrations of cyclic nucleotides upon one- and two-photon photolysis
(Chemical Equation Presented) Shedding light: Efficient activation of cyclic nucleoside monophosphates (cNMPs) can be achieved upon one- and two-photon flash photolysis of novel photolabile coumarinylmethyl esters of cAMP and cGMP (A = adenosine, G = guanosine) as well as their 8-bromosubstituted derivatives. The phototriggers show high solubility in water and permit space- and time-resolved investigations of the molecular mechanisms of cyclic nucleotide dependent processes.
Hagen, Volker,Dekowski, Brigitte,Nache, Vasilica,Schmidt, Reinhard,Geissler, Daniel,Lorenz, Dorothea,Eichhorst, Jenny,Keller, Sandra,Kaneko, Hiroshi,Benndorf, Klaus,Wiesner, Burkhard
p. 7887 - 7891
(2007/10/03)

Chemical synthesis and biological activity of 8-substituted adenosine 3',5'-cyclic monophosphate derivatives.
-
Muneyama et al.
p. 2390,2391,2392
(2007/10/10)

More Articles about upstream products of 23583-48-4

60-92-4
cAMP

More Articles about downstream products of 23583-48-4

Chemical Properties

Melting Point: 254 °C (dec.)(lit.)
Boiling Point: 741.9 °C at 760 mmHg
Flash Point:402.5 °C
Density: 2.8 g/cm³
Solubility:aqueous base: soluble
Storage Temp.:−20°C
PKA: 0.95±0.60(Predicted)
Sensitive: Hygroscopic
BRN: 591930
PSA: 164.65000
LogP: 0.52630

Show more

Global suppliers and manufacturers of 23583-48-4total 18 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Dayang Chem (Hangzhou) Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 3.0-3.0 / Kilogram
Main Products:994
Country:

Zhuozhou Wenxi import and Export Co., Ltd
Business Type:Trading Company
Min Order:1 Kilogram
FOB Price:USD $ 139.0-210.0 / Kilogram
Main Products:1
Country:

NewCan Biotech Limited
Business Type:Trading Company
Min Order:1 Milligram
FOB Price:No Data
Main Products:30
Country:

Zibo Hangyu Biotechnology Development Co., Ltd
Business Type:Lab/Research institutions
Min Order:10 Gram
FOB Price:No Data
Main Products:313
Country:

Zibo Dorne chemical technology co. LTD
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:70
Country:

Xiamen Jenny Chemical Technology Co., Ltd.
Business Type:Trading Company
Min Order:1 Milligram
FOB Price:No Data
Main Products:33
Country:

Shandong Mopai Biotechnology Co., LTD
Business Type:Lab/Research institutions
Min Order:1 Gram
FOB Price:No Data
Main Products:60
Country:

Hunan chemfish Pharmaceutical co.,Ltd
Business Type:Manufacturers
Min Order:No Data
FOB Price:No Data
Main Products:29
Country:

Antimex Chemical Limied
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:163
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

Chemlyte Solutions
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:198
Country:

Chemsigma International Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:84
Country:

ZHEJIANG JIUZHOU CHEM CO.,LTD
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:27
Country:

NUTROCHEM- MANUFACTURE PLACE
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Wuhan MoonZY Biological Technology Co.,Ltd
Business Type:Lab/Research institutions
Min Order:1 Milligram
FOB Price:No Data
Main Products:1
Country:

Wuxi Morality Chemical Co., Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

yuyongmei
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

BIOLOG
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 23583-48-4

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer